Actor (145 credits)
- Super Troopers 2 (2018) Guy Le Franc
- The Orville (2017) Darulio
- How to Be a Latin Lover (2017)
- 73rd Golden Globe Awards (2016) играет самого себя - номинант
- The Lion Guard (2016) Simba, voice acting
- Comedy Central Roast of Rob Lowe (2016)
- Monster Trucks (2016)
- The 67th Primetime Emmy Awards (2015) играет самого себя - презентатор: Outstanding Lead Actress in a Limited Series or Movie
- The Lion Guard: Return of the Roar (2015) Simba, voice acting
- Moonbeam City (2015) Dazzle Novak
- Pocket Listing (2015) Frank Hunter
- The Grinder (2015) Dean Sanderson
- Code Black (2015) Dr. Ethan Willis
- Basic Cable with George & Monty (2015) играет самого себя
- You, Me and the Apocalypse (2015) Father Jude
- 20th Annual Screen Actors Guild Awards (2014) играет самого себя - презентатор / Nominee
- Beautiful & Twisted (2014) Ben Novack Jr.
- 71st Golden Globe Awards (2014) играет самого себя - номинант, not listed in credits
- The Interview (2014) Rob Lowe, not listed in credits
- The '90s: The Last Great Decade? (мини-сериал) (2014) играет самого себя, рассказчик
- Against the Odds (2014) рассказчик
- Sex Tape (2014) Hank
- The Pro (2014) Ben Bertrahm
- Prosecuting Casey Anthony (2013) Jeff Ashton
- The '80s: The Decade That Made Us (2013) рассказчик
- Behind the Candelabra (2013) Dr. Jack Startz
- Killing Kennedy (2013) John F. Kennedy
- Oprah's Next Chapter (2012) играет самого себя
- The 69th Annual Golden Globe Awards (2012) играет самого себя - презентатор: Best Actress in a Mini-Series or TV-Movie
- Drew Peterson: Untouchable (2012) Drew Peterson
- Knife Fight (2012) Paul Turner
- Parks and Recreation: Dammit Jerry! (2012) Chris Traeger
- I Melt with You (2011) Jonathan
- The 63rd Primetime Emmy Awards (2011) играет самого себя - Co-Presenter: Outstanding Lead Actress in a Comedy Series
- Franklin & Bash (2011) Rob Lowe
- Piers Morgan Tonight (2011) играет самого себя - гость
- Breakaway (2011) Dan Winters
- WWII in HD: The Air War (2010) рассказчик, voice acting
- Stand Up to Cancer (2010) играет самого себя
- Young Justice (2010) Captain Marvel
- Who Do You Think You Are? (2010) играет самого себя
- 30 for 30 (2009) рассказчик
- The 61st Primetime Emmy Awards (2009) играет самого себя - презентатор: Outstanding Lead Actor in a Comedy Series
- The Invention of Lying (2009) Brad Kessler
- Parks and Recreation (2009) Chris Traeger
- Too Late to Say Goodbye (2009) Bart Corbin
- Prequel: The Dawn of Lying (2009)
- Streisand: Live in Concert (2009) играет самого себя - Audience, not listed in credits
- The 80th Annual Academy Awards (2008) играет самого себя, хроника, not listed in credits
- Stand Up to Cancer (2008) играет самого себя
- For the Bible Tells Me So (2007) Sam Seaborn, хроника
- TMZ on TV (2007) играет самого себя
- Californication (2007)
- Stir of Echoes: The Homecoming (2007)
- 100 Greatest Teen Stars (2006) играет самого себя, хроника
- Brothers & Sisters (2006)
- Celebrity Sex Tapes Unwound (2006) хроника
- A Perfect Day (2006) Rob Harlan
- The Christmas Blessing (2005) Robert Layton
- Beach Girls (мини-сериал) (2005) Jack Kilvert
- Tsunami Aid: A Concert of Hope (2005) играет самого себя
- Thank You for Smoking (2005) Jeff Megall
- The Friday Night Project (2005) играет самого себя - гость ведущий
- Jiminy Glick in Lalawood (2004) играет самого себя
- Dr. Vegas (2004) Dr. Billy Grant
- Retrosexual: The 80's (2004) хроника
- Salem's Lot (2004) Ben Mears
- The Insider (2004) играет самого себя
- Perfect Strangers (2004) Lloyd Rockwell
- 101 Most Shocking Moments in Entertainment (2003) играет самого себя, хроника
- The 55th Annual Primetime Emmy Awards (2003) играет самого себя - Co-Presenter
- I Love the '80s Strikes Back (2003) играет самого себя
- View from the Top (2003) Co-Pilot Steve Bench
- Jimmy Kimmel Live! (2003) играет самого себя - гость
- The Lyon's Den (2003) John «Jack» Turner
- The 54th Annual Primetime Emmy Awards (2002) играет самого себя
- 8th Annual Screen Actors Guild Awards (2002) играет самого себя
- The West Wing Documentary Special (2002) Sam Seaborn
- Austin Powers in Goldmember (2002) Middle Number Two
- Framed (2002) Mike Santini
- Founding Brothers (2002) James Madison, voice acting
- The Christmas Shoes (2002) Robert Layton
- 7th Annual Screen Actors Guild Awards (2001) играет самого себя
- The 58th Annual Golden Globe Awards (2001) играет самого себя - номинант
- Proximity (2001) William Conroy
- Primetime Glick (2001) играет самого себя
- Jane Doe (2001) David Doe
- The 57th Annual Golden Globe Awards (2000) играет самого себя - номинант: Best Actor in a TV-Series Drama
- The 26th Annual People's Choice Awards (2000) играет самого себя - презентатор
- CBS Cares (2000) играет самого себя
- Saturday Night Live: Game Show Parodies (2000) играет самого себя, хроника, not listed in credits
- Under Pressure (2000) John Spencer
- The Specials (2000) The Weevil
- One Hell of a Guy (2000) Nick
- Winding Roads (1999) Partygoer
- Atomic Train (1999) John Seger
- Dead Silent (1999) Kevin Finney
- Hollywood Salutes Jodie Foster: An American Cinematheque Tribute (1999) играет самого себя
- Austin Powers: The Spy Who Shagged Me (1999) Young Number Two
- The West Wing (1999) Sam Seaborn, $ 100 000
- Outrage (1998) Tom Casey
- For Hire (1998) Mitch Lawrence
- Crazy Six (1997) Billie, a.k.a. Crazy Six
- Contact (1997) Richard Rank
- Living in Peril (1997) Walter Woods
- Hostile Intent (1997) Cleary
- Midnight Man (1997) Sean Dillon
- Austin Powers: International Man of Mystery (1997) Decapitated Henchman's Friend, not listed in credits
- On Dangerous Ground (1996) Sean Dillon
- Fox Hunt (1996) Edison Pettibone
- Mulholland Falls (1995) Hoodlum, not listed in credits
- The Naked Truth (1995) играет самого себя
- First Degree (1995) Det. Rick Mallory
- Tommy Boy (1995) Paul Barish, not listed in credits
- Frank & Jesse (1995)
- Extra (1994) играет самого себя
- The Stand (1994) Nick Andros
- Wayne's World (1992) Benjamin Oliver
- The Finest Hour (1992) Lawrence Hammer
- The Larry Sanders Show (1992) Rob Lowe
- The Dark Backward (1991) Dirk Delta
- Bad Influence (1990) Alex
- Un dia és un dia (1990) играет самого себя - гость
- If the Shoe Fits (1990) Francesco Salvitore
- The 61st Annual Academy Awards (1989) играет самого себя - исполнитель
- The 14th Annual People's Choice Awards (1988) играет самого себя - Co-Presenter: Favourite Drama Motion Picture
- The 45th Annual Golden Globe Awards (1988) играет самого себя - номинант: лучшая мужская роль второго плана
- The 60th Annual Academy Awards (1988) играет самого себя - Co-Presenter: Best Film Editing
- Masquerade (1988)
- Illegally Yours (1988) Richard Dice
- The Last Resort with Jonathan Ross (1987) играет самого себя - гость
- Square Dance (1987)
- About Last Night... (1986) Danny
- Youngblood (1986) Dean Youngblood
- The 42nd Annual Golden Globe Awards (1985) играет самого себя - презентатор
- St. Elmo's Fire (1985) Billy Hicks
- John Parr: St. Elmo's Fire (Man in Motion) (1985) Billy Hicks
- The 41st Annual Golden Globe Awards (1984) играет самого себя - номинант: Лучшая мужская роль второго плана in a Series, Mini-Series or Motion Picture Made for TV
- Oxford Blues (1984)
- The Hotel New Hampshire (1984)
- The Go-Go's: Turn to You (1984) Man
- Thursday's Child (1983) Sam Alden
- The Outsiders (1983) Sodapop Curtis
- Class (1983) Skip
- ABC Afterschool Specials (1972) Charles Elderberry
Director (1 credits)
Producer (9 credits)
Writer (1 credits)
