Actor (108 credits)
- The Untold Tales of Armistead Maupin (2017) играет саму себя
- Sink Sank Sunk (2017) Mitzi Mills
- Ozark (2017) Wendy Byrde, $ 300 000
- Red Nose Day Actually (2017) Sarah
- The Dinner (2017) Claire Lohman
- Genius (2016)
- Sully (2016) Lorrie Sullenberger
- Teenage Mutant Ninja Turtles: Out of the Shadows (2016) Chief Vincent
- Nocturnal Animals (2016)
- Mr. Holmes (2015) Mrs. Munro
- Red Nose Day (2015) играет саму себя
- Last Week Tonight with John Oliver (2014) Florence Harding
- The Fifth Estate (2013) Sarah Shaw
- The 65th Primetime Emmy Awards (2013) играет саму себя - Winner: Outstanding Lead Actress in a Miniseries or a Movie, хроника (credit only)
- Inside Amy Schumer (2013) Laura Linney
- Letters to Jackie: Remembering President Kennedy (2013) играет саму себя - рассказчик
- Aimee Mann: Charmer (2012) Robot Aimee Mann
- The 69th Annual Golden Globe Awards (2012) играет саму себя - номинантка: Best Actress in a TV Series - Comedy or Musical
- Enduring Legacy (2012) Abigail Adams, voice acting
- Hyde Park on Hudson (2012) Daisy
- The 63rd Primetime Emmy Awards (2011) играет саму себя - Nominated: Outstanding Lead Actress in a Comedy Series
- Arthur Christmas (2011) North Pole Computer, voice acting
- The Details (2011) Lila
- Morning (2010)
- The 64th Annual Tony Awards (2010) играет саму себя - номинантка: Best Lead Actress in a Play & Presenter
- Sympathy for Delicious (2010) Nina Hogue
- Stand Up to Cancer (2010) играет саму себя
- The Big C (2010) Cathy Jamison
- 15th Annual Screen Actors Guild Awards (2009) играет саму себя - Winner Female Actor in a Television Movie or Miniseries
- The 66th Annual Golden Globe Awards (2009) играет саму себя - Winner: Best Actress in a Mini-Series or a Motion Picture Made for Television
- The City of Your Final Destination (2009) Caroline
- We Are One: The Obama Inaugural Celebration at the Lincoln Memorial (2009) играет саму себя
- Watch What Happens: Live (2009) играет саму себя
- Oscar, que empiece el espectáculo (2008) Annabeth Markum, хроника, not listed in creditsа
- The 80th Annual Academy Awards (2008) играет саму себя - номинантка: Лучшая женская роль
- The 60th Primetime Emmy Awards (2008) играет саму себя - Winner: Outstanding Lead Actress in a Miniseries or a Movie
- The 62nd Annual Tony Awards (2008) играет саму себя - презентатор: Best Featured Actor in a Play
- Ceremonia de inauguración - 56º Festival internacional de cine de San Sebastián (2008) Lisa, хроника, not listed in creditsа
- Speechless (2008) играет саму себя
- John Adams (2008) Abigail Adams
- The Other Man (2008) Lisa
- La noche de los Oscar (2008) играет саму себя
- The Savages (2007) Wendy Savage
- The Nanny Diaries (2007) Mrs. X
- The 63rd Annual Golden Globe Awards (2006) играет саму себя - номинантка: Best Actress in a Motion Picture - Musical or Comedy
- The Megan Mullally Show (2006) играет саму себя - гость
- Armenian Genocide (2006) Maria Jacobsen, voice acting
- The Hottest State (2006) Jesse
- Driving Lessons (2006) Laura
- Man of the Year (2006) Eleanor Green
- Breach (2006) Kate Burroughs
- 2006 Independent Spirit Awards (2006) играет саму себя
- 11th Annual Screen Actors Guild Awards (2005) играет саму себя
- The 59th Annual Tony Awards (2005) играет саму себя - номинантка: Best Actress in a Play & Presenter: Memorial Tribute
- The 62nd Annual Golden Globe Awards (2005) играет саму себя - номинантка: Best Supporting Actress in a Motion Picture
- The 77th Annual Academy Awards (2005) играет саму себя - номинантка: Best Supporting Actress & Presenter: Best Animated Short
- Jindabyne (2005)
- The Exorcism of Emily Rose (2005) Erin Bruner
- The Squid and the Whale (2005) Joan Berkman
- 10th Annual Screen Actors Guild Awards (2004) играет саму себя
- The 56th Annual Primetime Emmy Awards (2004) играет саму себя - Winner: Outstanding Guest Actress in a Comedy Series / Co-Presenter: Best Director of a Comedy Series
- The 58th Annual Tony Awards (2004) играет саму себя - презентатор: Best Revival of a Play
- Kinsey (2004) Clara McMillen
- P.S. (2004) Louise Harrington
- Frasier: Analyzing the Laughter (2004) Charlotte, хроника, not listed in creditsа
- The 2004 IFP/West Independent Spirit Awards (2004) играет саму себя - презентатор: Special Distinction Award
- Moving Image Salutes Richard Gere (2004) играет саму себя
- The 60th Annual Golden Globe Awards (2003) играет саму себя - презентатор: Best Mini-Series or Motion Picture Made for Television
- Love Actually (2003) Sarah
- Day by Day: A Director's Journey Part I (2003) играет саму себя
- Sunday Morning Shootout (2003) играет саму себя
- Mystic River (2003) Annabeth Markum
- The 56th Annual Tony Awards (2002) играет саму себя - номинантка
- Gala Paramount Pictures Celebrates 90th Anniversary with 90 Stars for 90 Years (2002) играет саму себя
- The Life of David Gale (2002) Constance Harraway
- The Laramie Project (2002) Sherry Johnson
- Wild Iris (2001) Iris Bravard
- 7th Annual Screen Actors Guild Awards (2001) играет саму себя - номинантка: Outstanding Performance by a Female Actor in a Leading Role / Co-presenter: Outstanding Performance by a Male Actor in a Supporting Role
- The 73rd Annual Academy Awards (2001) играет саму себя - номинантка: Лучшая женская роль
- You Can Count on Me: A Look Inside (2001)
- The Mothman Prophecies (2001) Connie Mills
- Further Tales of the City (2001) Mary Ann Singleton
- The 2001 IFP/West Independent Spirit Awards (2001) играет саму себя, not listed in creditsа
- The House of Mirth (2000) Bertha Dorset
- Running Mates (2000) Lauren Hartman
- Maze (2000)
- You Can Count on Me (2000) Samantha «Sammy» Prescott, $ 10 000
- Lush (1999) Rachel Van Dyke
- Love Letters (1999) Melissa Gardner Cobb
- The Truman Show (1998) Meryl Burbank / Hannah Gill
- Armistead Maupin's More Tales of the City (1998) Mary Ann Singleton
- King of the Hill (1997) Marlene
- Absolute Power (1996) Kate Whitney
- El Magacine (1996) играет саму себя
- Primal Fear (1996) Janet Venable
- Congo (1995) Dr. Karen Ross
- Inside the Actors Studio (1994) играет саму себя - гость
- A Simple Twist of Fate (1994) Nancy Lambert Newland
- Politically Incorrect (1993) играет саму себя
- Frasier (1993) Charlotte
- Class of '61 (1993) Lily Magraw
- Searching for Bobby Fischer (1993) School Teacher
- Armistead Maupin's Tales of the City (1993) Mary Ann Singleton
- Dave (1993) Randi
- Blind Spot (1993) Phoebe
- Lorenzo's Oil (1992) Young Teacher
- American Experience (1988) играет саму себя - рассказчик
- Masterpiece Theatre (1971) играет саму себя - ведущая
Producer (1 credits)